Danocrine is used to treat cutaneous, abdominal, laryngeal attacks in females.

Danocrine capsules

Packet of medicine Danocrine (danazol) capsules 100 mg

Composition of Danocrine

It is a man-made steroid which is an ethisterone derivative. It is a crystalline powder which is white to light yellow in color. The molecular formula is C22H27NO2 with a molecular weight of 337.46 g. The inactive ingredients present in danocrine are: lactose, corn starch, talc and magnesium stearate.


This drug is used to cure infertility and pelvic pain due to endometriosis (uterine disorder) and also to treat tenderness/pain/nodules in the breast due to fibrocystic breast disorder. It is also used during specific congenital disease i.e. hereditary angioedema to prevent the inflammation of legs/arms/face/abdomen/airway. To treat fibrocystic breast disorder and endometriosis, this drug works by reducing the ovarian hormone level. These hormones actually worsen the conditions. To cure angioedema, danocrine works by raising the amount of some protein in the immune system of your body.

How to use Danocrine

This medicine has to be taken twice in a day by mouth. And the regular use of this drug would show high benefits. The doctor prescribes danocrine for you on the basis of your medical condition and drug interactions. Take this medicine with/without meals, what is most important is to select one way and repeat it in the same manner every day. This medicine in child bearing females should be started during menstruation. If not then they should be not be pregnant before the use of this drug.

Side-effects of Danocrine

Changes in voice, weight gain, flushing, and acne, unusual hair growth in body, reduced breast size or vaginal irritation/dryness may commonly occur. Some serious side-effects are listed below for which inform the doctor instantly:

  • Swollen ankles/hands/feet
  • Nervousness
  • Emotional instability
  • Hepatic toxicity
  • Jaundice
  • Changes in appetite
  • Muscle cramps
  • Joint pain
  • Eosinophilia
  • Hematuria
  • Constipation
  • Gastroenteritis
  • Back pain
  • Reversible erythrocytosis
  • Thrombocytopenia
  • Change in libido
  • Tachycardia
  • Myocardial infarction
  • Menstrual variation
  • Mood swings
  • Allergies
  • Bleeding gums
  • Malignant liver tumors
  • Interstitial pneumonitis
  • Sun sensitivity
  • Palpitation
  • Anxiety
  • Edema
  • Hair loss
  • Trouble breathing
  • Extreme dizziness
  • Sore throat
  • Seborrhea
  • Decreased estrogen level
  • Mild hirsutism

Contraindications of Danocrine

It is necessary to inform the doctor about your past health disorders, which includes: hypertension, blood vessel/heart disorders, breast cancer, kidney disease, liver problems, seizures, migraine, abnormal bleeding in vagina, prostate cancer or some blood disorders like polycythemia and porphyria. Don’t take this medicine if you are allergic to danozol. It is highly contraindicated during breast feeding and pregnancy. It may also cause androgen-dependent cancer.

Danocrine in pregnancy

Use of danocrine during pregnancy is strictly not allowed as it may be harmful for the fetus (unborn baby). It is not certain whether the drug is excreted into the breast milk or not.